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Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle

The mechanisms that lead to variation in human skin and hair color are not fully understood. To better understand the molecular control of skin and hair color variation, we modulated the expression of Tyrosinase (Tyr), which controls the rate-limiting step of melanogenesis, by expressing a single-co...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Paterson, Elyse K., Fielder, Thomas J., MacGregor, Grant R., Ito, Shosuke, Wakamatsu, Kazumasa, Gillen, Daniel L., Eby, Victoria, Boissy, Raymond E., Ganesan, Anand K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664286/
https://ncbi.nlm.nih.gov/pubmed/26619124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143702
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