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Comprehensive Evaluation of Commercial Bisulfite-Based DNA Methylation Kits and Development of an Alternative Protocol With Improved Conversion Performance

DNA methylation is the most studied epigenetic modification with a wide range of regulatory functions in mammalian genomes. It almost exclusively resides on CpG dinucleotides and, among others, plays important roles in early embryo development, onset, and maintenance of cancer. During the past 3 dec...

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Dettagli Bibliografici
Pubblicato in:Genet Epigenet
Autori principali: Tierling, Sascha, Schmitt, Beate, Walter, Jörn
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888801/
https://ncbi.nlm.nih.gov/pubmed/29636635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179237X18766097
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