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A combined HM-PCR/SNuPE method for high sensitive detection of rare DNA methylation

BACKGROUND: DNA methylation changes are widely used as early molecular markers in cancer detection. Sensitive detection and classification of rare methylation changes in DNA extracted from circulating body fluids or complex tissue samples is crucial for the understanding of tumor etiology, clinical...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tierling, Sascha, Schuster, Matthias, Tetzner, Reimo, Walter, Jörn
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887863/
https://ncbi.nlm.nih.gov/pubmed/20525169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-3-12
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