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Calcium(ii)-catalyzed enantioselective conjugate additions of amines

The direct enantioselective chiral calcium(ii)·phosphate complex (Ca[CPA](2))-catalyzed conjugate addition of unprotected alkyl amines to maleimides was developed. This mild catalytic system represents a significant advance towards the general convergent asymmetric amination of α,β-unsaturated elect...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Uno, Brice E., Dicken, Rachel D., Redfern, Louis R., Stern, Charlotte M., Krzywicki, Greg G., Scheidt, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887857/
https://ncbi.nlm.nih.gov/pubmed/29675209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05205g
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