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Novel bifunctional sulfonamides catalyze an enantioselective conjugate addition

A new bifunctional organocatalyst with a novel structural and functional motif has been developed. This bifunctional sulfonamide organocatalyst was used in the conjugate addition of 1,3-dicarbonyl compounds (13) to β-nitrostyrenes (12). Yields up to 91% and enantiomeric excesses up to 79% were obtai...

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Detalhes bibliográficos
Main Authors: McGarraugh, Patrick G., Brenner, Stacey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659672/
https://ncbi.nlm.nih.gov/pubmed/20066026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.11.027
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