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F40. NEUREXIN-1α (NRNX1α) HYPOFUNCTION INDUCES SCHIZOPHRENIA-RELEVANT DEFICITS IN CEREBRAL METABOLISM, COGNITIVE PROCESSING SPEED AND COGNITIVE FLEXIBILITY
BACKGROUND: Heterozygous deletions in NEUREXIN-1 (NRXN1) substantially increase the risk of developing schizophrenia (SZ) (Rujescu et al., 2009. Hum Mol Genet 18(5):988–96). We currently have little understanding into the mechanisms by which NRXN1 impacts on the brain to increase the risk of develop...
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| 發表在: | Schizophr Bull |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5887798/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby017.571 |
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