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High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2

The cardioprotective lipoprotein HDL (high-density lipoprotein) prevents myocardial infarction and cardiomyocyte death due to ischemia/reperfusion injury. The scavenger receptor class B, type 1 (SR-B1) is a high-affinity HDL receptor and has been shown to mediate HDL-dependent lipid transport as wel...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Durham, Kristina K., Chathely, Kevin M., Trigatti, Bernardo L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887020/
https://ncbi.nlm.nih.gov/pubmed/29523748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170703
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