High-density lipoprotein inhibits mechanical stress-induced cardiomyocyte autophagy and cardiac hypertrophy through angiotensin II type 1 receptor-mediated PI3K/Akt pathway

Mechanical stress triggers cardiac hypertrophy and autophagy through an angiotensin II (Ang II) type 1 (AT1) receptor-dependent mechanism. Low level of high density lipoprotein (HDL) is an independent risk factor for cardiac hypertrophy. This study was designed to evaluate the effect of HDL on mecha...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lin, Li, Liu, Xuebo, Xu, Jianfeng, Weng, Liqing, Ren, Jun, Ge, Junbo, Zou, Yunzeng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549043/
https://ncbi.nlm.nih.gov/pubmed/25946687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12567
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