High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists

HDL carries biologically active lipids such as sphingosine-1-phosphate (S1P) and stimulates a variety of cell signaling pathways in diverse cell types, which may contribute to its ability to protect against atherosclerosis. HDL and sphingosine-1-phosphate receptor agonists, FTY720 and SEW2871 trigge...

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Autors principals: Al-Jarallah, Aishah, Chen, Xing, González, Leticia, Trigatti, Bernardo L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154704/
https://ncbi.nlm.nih.gov/pubmed/25188469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106487
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