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Sildenafil ameliorates right ventricular early molecular derangement during left ventricular pressure overload

Right ventricular (RV) dysfunction following left ventricular (LV) failure is associated with poor prognosis. RV remodeling is thought initiated by the increase in the afterload of RV due to secondary pulmonary hypertension (PH) to impaired LV function; however, RV molecular changes might occur in e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Imai, Yousuke, Kariya, Taro, Iwakiri, Masaki, Yamada, Yoshitsugu, Takimoto, Eiki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886579/
https://ncbi.nlm.nih.gov/pubmed/29621314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195528
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