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Sildenafil ameliorates right ventricular early molecular derangement during left ventricular pressure overload

Right ventricular (RV) dysfunction following left ventricular (LV) failure is associated with poor prognosis. RV remodeling is thought initiated by the increase in the afterload of RV due to secondary pulmonary hypertension (PH) to impaired LV function; however, RV molecular changes might occur in e...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Imai, Yousuke, Kariya, Taro, Iwakiri, Masaki, Yamada, Yoshitsugu, Takimoto, Eiki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886579/
https://ncbi.nlm.nih.gov/pubmed/29621314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195528
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