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Sildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine heart failure model
AIM: Sildenafil, a phosphodiesterase 5 (PDE5) inhibitor, has been shown to exert beneficial effects in heart failure. The purpose of this study was to test whether sildenafil suppressed transverse-tubule (T-tubule) remodeling in left ventricular (LV) failure and thereby providing the therapeutic ben...
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| Publicat a: | Acta Pharmacol Sin |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820805/ https://ncbi.nlm.nih.gov/pubmed/26972492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.13 |
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