Sildenafil ameliorates left ventricular T-tubule remodeling in a pressure overload-induced murine heart failure model

AIM: Sildenafil, a phosphodiesterase 5 (PDE5) inhibitor, has been shown to exert beneficial effects in heart failure. The purpose of this study was to test whether sildenafil suppressed transverse-tubule (T-tubule) remodeling in left ventricular (LV) failure and thereby providing the therapeutic ben...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Pharmacol Sin
Prif Awduron: Huang, Chun-kai, Chen, Bi-yi, Guo, Ang, Chen, Rong, Zhu, Yan-qi, Kutschke, William, Hong, Jiang, Song, Long-sheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820805/
https://ncbi.nlm.nih.gov/pubmed/26972492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.13
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