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Liver-directed gene therapy for murine glycogen storage disease type Ib
Glycogen storage disease type-Ib (GSD-Ib), deficient in the glucose-6-phosphate transporter (G6PT), is characterized by impaired glucose homeostasis, myeloid dysfunction, and long-term risk of hepatocellular adenoma (HCA). We examined the efficacy of G6PT gene therapy in G6pt−/− mice using recombina...
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| Publicado no: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886224/ https://ncbi.nlm.nih.gov/pubmed/28973635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx325 |
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