Sub-nanosecond tryptophan radical deprotonation mediated by a protein-bound water cluster in class II DNA photolyases

Class II DNA photolyases are flavoenzymes occurring in both prokaryotes and eukaryotes including higher plants and animals. Despite considerable structural deviations from the well-studied class I DNA photolyases, they share the main biological function, namely light-driven repair of the most common...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Müller, Pavel, Ignatz, Elisabeth, Kiontke, Stephan, Brettel, Klaus, Essen, Lars-Oliver
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2017
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885780/
https://ncbi.nlm.nih.gov/pubmed/29675165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03969g
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