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Sub-nanosecond tryptophan radical deprotonation mediated by a protein-bound water cluster in class II DNA photolyases

Class II DNA photolyases are flavoenzymes occurring in both prokaryotes and eukaryotes including higher plants and animals. Despite considerable structural deviations from the well-studied class I DNA photolyases, they share the main biological function, namely light-driven repair of the most common...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Müller, Pavel, Ignatz, Elisabeth, Kiontke, Stephan, Brettel, Klaus, Essen, Lars-Oliver
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885780/
https://ncbi.nlm.nih.gov/pubmed/29675165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03969g
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