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Kinetics of cyclobutane thymine dimer splitting by DNA photolyase directly monitored in the UV
CPD photolyase uses light to repair cyclobutane pyrimidine dimers (CPDs) formed between adjacent pyrimidines in UV-irradiated DNA. The enzyme harbors an FAD cofactor in fully reduced state (FADH(-)). The CPD repair mechanism involves electron transfer from photoexcited FADH(-) to the CPD, splitting...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111307/ https://ncbi.nlm.nih.gov/pubmed/21606324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101026108 |
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