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Circadian Rest-Activity Pattern Changes in Aging and Preclinical Alzheimer Disease

IMPORTANCE: Circadian rhythm disturbances occur in symptomatic Alzheimer disease (AD) and have been hypothesized to contribute to disease pathogenesis. However, it is unknown whether circadian changes occur during the presymptomatic phase of the disease. OBJECTIVE: To examine the associations betwee...

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Detaylı Bibliyografya
Yayımlandı:JAMA Neurol
Asıl Yazarlar: Musiek, Erik S., Bhimasani, Meghana, Zangrilli, Margaret A., Morris, John C., Holtzman, David M., Ju, Yo-El S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Medical Association 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885197/
https://ncbi.nlm.nih.gov/pubmed/29379963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.4719
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