Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial

IMPORTANCE: Therapeutic options are needed for patients with advanced gastric cancer whose disease has progressed after 2 or more lines of therapy. OBJECTIVE: To evaluate the safety and efficacy of pembrolizumab in a cohort of patients with previously treated gastric or gastroesophageal junction can...

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Pubblicato in:JAMA Oncol
Autori principali: Fuchs, Charles S., Doi, Toshihiko, Jang, Raymond W., Muro, Kei, Satoh, Taroh, Machado, Manuela, Sun, Weijing, Jalal, Shadia I., Shah, Manish A., Metges, Jean-Phillipe, Garrido, Marcelo, Golan, Talia, Mandala, Mario, Wainberg, Zev A., Catenacci, Daniel V., Ohtsu, Atsushi, Shitara, Kohei, Geva, Ravit, Bleeker, Jonathan, Ko, Andrew H., Ku, Geoffrey, Philip, Philip, Enzinger, Peter C., Bang, Yung-Jue, Levitan, Diane, Wang, Jiangdian, Rosales, Minori, Dalal, Rita P., Yoon, Harry H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2018
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885175/
https://ncbi.nlm.nih.gov/pubmed/29543932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.0013
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