Assessment of Pembrolizumab Therapy for the Treatment of Microsatellite Instability–High Gastric or Gastroesophageal Junction Cancer Among Patients in the KEYNOTE-059, KEYNOTE-061, and KEYNOTE-062 Clinical Trials

IMPORTANCE: Immunotherapy has been associated with improved outcomes among patients who have received previous treatment for microsatellite instability–high (MSI-H) tumors. OBJECTIVE: To evaluate the antitumor activity of pembrolizumab therapy vs chemotherapy among patients with MSI-H advanced gastr...

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Publicado en:JAMA Oncol
Autores principales: Chao, Joseph, Fuchs, Charles S., Shitara, Kohei, Tabernero, Josep, Muro, Kei, Van Cutsem, Eric, Bang, Yung-Jue, De Vita, Ferdinando, Landers, Gregory, Yen, Chia-Jui, Chau, Ian, Elme, Anneli, Lee, Jeeyun, Özgüroğlu, Mustafa, Catenacci, Daniel, Yoon, Harry H., Chen, Erluo, Adelberg, David, Shih, Chie-Schin, Shah, Sukrut, Bhagia, Pooja, Wainberg, Zev A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2021
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017478/
https://ncbi.nlm.nih.gov/pubmed/33792646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2021.0275
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