ロード中...
In Vivo-Selected Compensatory Mutations Restore the Fitness Cost of Mosaic penA Alleles That Confer Ceftriaxone Resistance in Neisseria gonorrhoeae
Resistance to ceftriaxone in Neisseria gonorrhoeae is mainly conferred by mosaic penA alleles that encode penicillin-binding protein 2 (PBP2) variants with markedly lower rates of acylation by ceftriaxone. To assess the impact of these mosaic penA alleles on gonococcal fitness, we introduced the mos...
保存先:
| 出版年: | mBio |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5885032/ https://ncbi.nlm.nih.gov/pubmed/29615507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01905-17 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|