Neisseria cinerea with High Ceftriaxone MIC Is a Source of Ceftriaxone and Cefixime Resistance-Mediating penA Sequences in Neisseria gonorrhoeae

Mosaic penA alleles have caused most of the cephalosporin resistance in Neisseria gonorrhoeae, but their evolution is mostly unknown. The penA gene from Neisseria cinerea strain AM1601 (ceftriaxone MIC, 1.0 μg/ml) caused ceftriaxone resistance (MIC, 1 μg/ml) in a ceftriaxone-susceptible gonococcal s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Igawa, Gene, Yamagishi, Yuka, Lee, Ken-Ichi, Dorin, Misato, Shimuta, Ken, Suematsu, Hiroyuki, Nakayama, Shu-Ichi, Mikamo, Hiroshige, Unemo, Magnus, Ohnishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826163/
https://ncbi.nlm.nih.gov/pubmed/29311079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02069-17
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