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High-risk TP53 mutations are associated with extra nodal extension in oral cavity squamous cell carcinoma

PURPOSE: Development of extra-nodal extension (ENE) has been associated with poor survival in patients with oral cavity squamous cell carcinoma (OSCC). Here we sought to confirm the role of ENE as a poor prognostic factor, and identify genomic and epigenetic markers of ENE in order to develop a pred...

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Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Sandulache, Vlad C., Michikawa, Chieko, Kataria, Pranav, Gleber-Netto, Frederico O., Bell, Diana, Trivedi, Sanchit, Rao, Xiayu, Wang, Jing, Zhao, Mei, Jasser, Samar, Myers, Jeffrey N., Pickering, Curtis R.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884733/
https://ncbi.nlm.nih.gov/pubmed/29330202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0721
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