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Replication-incompetent gammaretroviral and lentiviral vector-based insertional mutagenesis screens identify prostate cancer progression genes

Replication-incompetent gammaretroviral (γRV) and lentiviral (LV) vectors have both been used in insertional mutagenesis screens to identify cancer drivers. In this approach the vectors stably integrate in the host cell genome and induce cancers by dysregulating nearby genes. The cells that contain...

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Vydáno v:Oncotarget
Hlavní autoři: Bii, Victor M., Collins, Casey P., Hocum, Jonah D., Trobridge, Grant D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884640/
https://ncbi.nlm.nih.gov/pubmed/29643985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24503
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