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Lentiviral Vector-Mediated Insertional Mutagenesis Screen Identifies Genes that Influence Androgen Independent Prostate Cancer Progression and Predict Clinical Outcome

Prostate cancer (PC) is the second leading cause of cancer related deaths in US men. Androgen deprivation therapy (ADT) improves clinical outcome, but tumors often recur and progress to androgen independent prostate cancer (AIPC) which no longer responds to ADT. The progression to AIPC is due to gen...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Nalla, Arun K., Williams, Theodore F., Collins, Casey P., Rae, Dustin T., Trobridge, Grant D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393267/
https://ncbi.nlm.nih.gov/pubmed/26512949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22425
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