Lentiviral Vector-Mediated Insertional Mutagenesis Screen Identifies Genes that Influence Androgen Independent Prostate Cancer Progression and Predict Clinical Outcome

Prostate cancer (PC) is the second leading cause of cancer related deaths in US men. Androgen deprivation therapy (ADT) improves clinical outcome, but tumors often recur and progress to androgen independent prostate cancer (AIPC) which no longer responds to ADT. The progression to AIPC is due to gen...

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Bibliographic Details
Published in:Mol Carcinog
Main Authors: Nalla, Arun K., Williams, Theodore F., Collins, Casey P., Rae, Dustin T., Trobridge, Grant D.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393267/
https://ncbi.nlm.nih.gov/pubmed/26512949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22425
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