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DAF in diabetic patients is subject to glycation/inactivation at its active site residues()

Decay accelerating factor (DAF or CD55) is a cell associated C3 and C5 convertase regulator originally described in terms of protection of self-cells from systemic complement but now known to modulate adaptive T cell responses. It is expressed on all cell types. We investigated whether nonenzymatic...

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Publicado en:Mol Immunol
Autores principales: Flückiger, Rudolf, Cocuzzi, Enzo, Nagaraj, Ram H., Shoham, Menachem, Kern, Timothy S., Medof, M. Edward
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884443/
https://ncbi.nlm.nih.gov/pubmed/28886871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.06.036
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