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Dissecting PUGNAc-mediated inhibition of the pro-survival action of insulin
Previous studies utilizing PUGNAc, the most widely used β-N-acetylglucosaminidase (OGA) inhibitor to increase global O-N-acetylglucosamine (GlcNAc) levels, have reported a variety of effects including insulin resistance as a direct result of elevated O-GlcNAc levels. The notion of OGA inhibition cau...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Glycobiology |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884396/ https://ncbi.nlm.nih.gov/pubmed/27072814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cww043 |
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