Molecular Mechanisms of Tight Binding through Fuzzy Interactions

Many intrinsically disordered proteins (IDPs) form fuzzy complexes upon binding to their targets. Although many IDPs are weakly bound in fuzzy complexes, some IDPs form high-affinity complexes. One example is the nonstructural protein 1 (NS1) of the 1918 Spanish influenza A virus, which hijacks cell...

Full description

Saved in:
Bibliographic Details
Published in:Biophys J
Main Authors: Shen, Qingliang, Shi, Jie, Zeng, Danyun, Zhao, Baoyu, Li, Pingwei, Hwang, Wonmuk, Cho, Jae-Hyun
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2018
Subjects:
Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883614/
https://ncbi.nlm.nih.gov/pubmed/29590589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.031
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items