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Molecular Mechanisms of Tight Binding through Fuzzy Interactions

Many intrinsically disordered proteins (IDPs) form fuzzy complexes upon binding to their targets. Although many IDPs are weakly bound in fuzzy complexes, some IDPs form high-affinity complexes. One example is the nonstructural protein 1 (NS1) of the 1918 Spanish influenza A virus, which hijacks cell...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Shen, Qingliang, Shi, Jie, Zeng, Danyun, Zhao, Baoyu, Li, Pingwei, Hwang, Wonmuk, Cho, Jae-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883614/
https://ncbi.nlm.nih.gov/pubmed/29590589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.031
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