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Positive Feedback Mechanisms among Local Ca Releases, NCX, and I(CaL) Ignite Pacemaker Action Potentials
Recent data suggest that cardiac pacemaker cell function is determined by numerous time-, voltage-, and Ca-dependent interactions of cell membrane electrogenic proteins (M-clock) and intracellular Ca cycling proteins (Ca-clock), forming a coupled-clock system. Many aspects of the coupled-clock syste...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5883559/ https://ncbi.nlm.nih.gov/pubmed/29539403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.12.043 |
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