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RyR-NCX-SERCA local crosstalk ensures pacemaker cell function at rest and during the fight-or-flight reflex
RATIONALE: A recent study published in Circulation Research by Gao et al. employed SA node-targeted, incomplete Ncx1-knockout (KO) in mice to explore the role of the Na(+)/Ca(2+) exchanger (NCX) in cardiac pacemaker. The authors concluded that NCX is required for increasing sinus rates, but not for...
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| Publicado en: | Circ Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538700/ https://ncbi.nlm.nih.gov/pubmed/24158576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.302465 |
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