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TGF-β1 expression in regulatory NK1.1(-)CD4(+)NKG2D(+) T cells dependents on the PI3K-p85α/JNK, NF-κB and STAT3 pathways
NK1.1(-)CD4(+)NKG2D(+) cells exert their immune-regulatory function in tumor as an unconventional regulatory T cell subset through the production of TGF-β1; however, the molecular mechanisms involving with the activation of nuclear factors for TGF-β1 transcription remain unclear. Here we determined...
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| Gepubliceerd in: | Am J Cancer Res |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
e-Century Publishing Corporation
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5883098/ https://ncbi.nlm.nih.gov/pubmed/29637003 |
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