TGF-β1 expression in regulatory NK1.1(-)CD4(+)NKG2D(+) T cells dependents on the PI3K-p85α/JNK, NF-κB and STAT3 pathways

NK1.1(-)CD4(+)NKG2D(+) cells exert their immune-regulatory function in tumor as an unconventional regulatory T cell subset through the production of TGF-β1; however, the molecular mechanisms involving with the activation of nuclear factors for TGF-β1 transcription remain unclear. Here we determined...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Am J Cancer Res
Hlavní autoři: Han, Sen, Ding, Shizhen, Miao, Xin, Lin, Zhijie, Lu, Guotao, Xiao, Weiming, Ding, Yanbing, Qian, Li, Zhang, Yu, Jia, Xiaoqin, Zhu, Guoqiang, Gong, Weijuan
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883098/
https://ncbi.nlm.nih.gov/pubmed/29637003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky