Human fused NKG2D–IL-15 protein controls xenografted human gastric cancer through the recruitment and activation of NK cells

Interleukin (IL)-15 plays an important role in natural killer (NK) and CD8+ T-cell proliferation and function and is more effective than IL-2 for tumor immunotherapy. The trans-presentation of IL-15 by neighboring cells is more effective for NK cell activation than its soluble IL-15. In this study,...

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Publicado en:Cell Mol Immunol
Autores principales: Chen, Yan, Chen, Bei, Yang, Ti, Xiao, Weiming, Qian, Li, Ding, Yanbing, Ji, Mingchun, Ge, Xiaoqun, Gong, Weijuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360879/
https://ncbi.nlm.nih.gov/pubmed/26364916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.81
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