Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea

The ability of the human malarial parasite Plasmodium falciparum to adapt to environmental changes depends considerably on its ability to maintain within-population genetic variation. Strong selection, consequent to widespread antimalarial drug usage, occasionally elicits a rapid expansion of drug-r...

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Publicat a:Sci Rep
Autors principals: Mita, Toshihiro, Hombhanje, Francis, Takahashi, Nobuyuki, Sekihara, Makoto, Yamauchi, Masato, Tsukahara, Takahiro, Kaneko, Akira, Endo, Hiroyoshi, Ohashi, Jun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882878/
https://ncbi.nlm.nih.gov/pubmed/29615786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23811-7
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