ADAM17 inhibition enhances platinum efficiency in ovarian cancer

Chemotherapeutic resistance evolves in about 70 % of ovarian cancer patients and is a major cause of death in this tumor entity. Novel approaches to overcome these therapeutic limitations are therefore highly warranted. A disintegrin and metalloprotease 17 (ADAM17) is highly expressed in ovarian can...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hedemann, Nina, Rogmans, Christoph, Sebens, Susanne, Wesch, Daniela, Reichert, Manuel, Schmidt-Arras, Dirk, Oberg, Hans-Heinrich, Pecks, Ulrich, van Mackelenbergh, Marion, Weimer, Jörg, Arnold, Norbert, Maass, Nicolai, Bauerschlag, Dirk O.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882316/
https://ncbi.nlm.nih.gov/pubmed/29662625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24682
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