Combination of Enzastaurin and Pemetrexed Inhibits Cell Growth and Induces Apoptosis of Chemoresistant Ovarian Cancer Cells Regulating Extracellular Signal-Regulated Kinase 1/2 Phosphorylation

New strategies in the therapy for malignant diseases depend on a targeted influence on signal transduction pathways that regulate proliferation, cell growth, differentiation, and apoptosis by the activation of serine/threonine kinases. Enzastaurin (LY317615.HCl), a selective inhibitor of protein kin...

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Главные авторы: Bräutigam, Karen, Bauerschlag, Dirk Olaf, Weigel, Marion Tina, Biernath-Wüpping, Julia, Bauknecht, Thomas, Arnold, Norbert, Maass, Nicolai, Meinhold-Heerlein, Ivo
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press Inc. 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730140/
https://ncbi.nlm.nih.gov/pubmed/19701501
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