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Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence

Pioneer transcription factors specifically target their recognition DNA sequences within nucleosomes. FoxA is the pioneer transcription factor that binds to the ALB1 gene enhancer in liver precursor cells, and is required for liver differentiation in embryos. The ALB1 enhancer DNA sequence is report...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Open Biol
Hauptverfasser: Takizawa, Yoshimasa, Tanaka, Hiroki, Machida, Shinichi, Koyama, Masako, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Wade, Paul A., Wolf, Matthias, Kurumizaka, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881032/
https://ncbi.nlm.nih.gov/pubmed/29563192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170255
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