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Hypocretin Receptor 1 Knockdown in the Ventral Tegmental Area Attenuates Mesolimbic Dopamine Signaling and Reduces Motivation for Cocaine
The hypocretin receptor 1 (HCRTr1) is a critical participant in the regulation of motivated behavior. Previous observations demonstrate that acute pharmacological blockade of HCRTr1 disrupts dopamine (DA) signaling and the motivation for cocaine when delivered systemically or directly into the ventr...
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| Publicado no: | Addict Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880744/ https://ncbi.nlm.nih.gov/pubmed/28971565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12553 |
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