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Hypocretin receptor 1 blockade produces bimodal modulation of cocaine-associated mesolimbic dopamine signaling

RATIONALE: Cocaine addiction is a chronic psychiatric disorder characterized by pathological motivation to obtain cocaine and behavioral and neurochemical hypersensitivity to cocaine-associated cues. These features of cocaine addiction are thought to be driven by aberrant phasic dopamine signaling....

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Levy, KA, Brodnik, ZD, Shaw, JK, Perrey, DA, Zhang, Y, España, RA
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709206/
https://ncbi.nlm.nih.gov/pubmed/28667509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4673-y
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