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Suvorexant, an orexin/hypocretin receptor antagonist, attenuates motivational and hedonic properties of cocaine

Orexins (‘hypocretins’) are peptides produced by neurons of the hypothalamus that project to structures implicated in reward and emotion processing. Converging evidence demonstrates functional roles of orexin signaling in arousal, sleep/wakefulness, and motivated behaviors for natural and drug rewar...

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Publicat a:Addict Biol
Autors principals: Gentile, Taylor A., Simmons, Steven J., Barker, David J., Shaw, Jessica K., España, Rodrigo A., Muschamp, John W.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645207/
https://ncbi.nlm.nih.gov/pubmed/28419646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12507
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