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Suvorexant, an orexin/hypocretin receptor antagonist, attenuates motivational and hedonic properties of cocaine

Orexins (‘hypocretins’) are peptides produced by neurons of the hypothalamus that project to structures implicated in reward and emotion processing. Converging evidence demonstrates functional roles of orexin signaling in arousal, sleep/wakefulness, and motivated behaviors for natural and drug rewar...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Gentile, Taylor A., Simmons, Steven J., Barker, David J., Shaw, Jessica K., España, Rodrigo A., Muschamp, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645207/
https://ncbi.nlm.nih.gov/pubmed/28419646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12507
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