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Chemo- and Regioselective Lysine Modification on Native Proteins

[Image: see text] Site-selective chemical conjugation of synthetic molecules to proteins expands their functional and therapeutic capacity. Current protein modification methods, based on synthetic and biochemical technologies, can achieve site selectivity, but these techniques often require extensiv...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Matos, Maria J., Oliveira, Bruno L., Martínez-Sáez, Nuria, Guerreiro, Ana, Cal, Pedro M. S. D., Bertoldo, Jean, Maneiro, María, Perkins, Elizabeth, Howard, Julie, Deery, Michael J., Chalker, Justin M., Corzana, Francisco, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880509/
https://ncbi.nlm.nih.gov/pubmed/29473744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b12874
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