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Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides

LCAT is an enzyme responsible for the formation of cholesteryl esters from unesterified cholesterol (UC) and phospholipid (PL) molecules in HDL particles. However, it is poorly understood how LCAT interacts with lipoproteins and how apoA-I activates it. Here we have studied the interactions between...

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Casteleijn, Marco G., Parkkila, Petteri, Viitala, Tapani, Koivuniemi, Artturi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880497/
https://ncbi.nlm.nih.gov/pubmed/29438987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082685
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