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Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides

LCAT is an enzyme responsible for the formation of cholesteryl esters from unesterified cholesterol (UC) and phospholipid (PL) molecules in HDL particles. However, it is poorly understood how LCAT interacts with lipoproteins and how apoA-I activates it. Here we have studied the interactions between...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Casteleijn, Marco G., Parkkila, Petteri, Viitala, Tapani, Koivuniemi, Artturi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880497/
https://ncbi.nlm.nih.gov/pubmed/29438987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082685
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