Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide

α-Synuclein (α-syn) is a major component of Lewy bodies found in synucleinopathies including Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Under the pathological conditions, α-syn tends to generate a diverse form of aggregates showing toxicity to neuronal cells and able to transmit a...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Choi, Mal-Gi, Kim, Mi Jin, Kim, Do-Geun, Yu, Ri, Jang, You-Na, Oh, Won-Jong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880409/
https://ncbi.nlm.nih.gov/pubmed/29608598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195339
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