Individuals with sickle cell disease have a significantly greater vasoconstriction response to thermal pain than controls and have significant vasoconstriction in response to anticipation of pain

The painful vaso-occlusive crises (VOC) that characterize sickle cell disease (SCD) progress over hours from the asymptomatic steady-state. SCD patients report that VOC can be triggered by stress, cold exposure and pain itself. We anticipated that pain could cause neural-mediated vasoconstriction, d...

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Vydáno v:Am J Hematol
Hlavní autoři: Khaleel, Maha, Puliyel, Mammen, Shah, Payal, Sunwoo, John, Kato, Roberta M., Chalacheva, Patjanaporn, Thuptimdang, Wanwara, Detterich, Jon, Wood, John C, Tsao, Jennie, Zeltzer, Lonnie, Sposto, Richard, Khoo, Michael C.K., Coates, Thomas D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880319/
https://ncbi.nlm.nih.gov/pubmed/28707371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24858
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