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Losartan Attenuates Degradation of Aorta and Lung Tissue Micromechanics in a Mouse Model of Severe Marfan Syndrome

Marfan syndrome (MFS) is an autosomal dominant disease of the connective tissue due to mutations in the fibrillin-1 gene (FBN1). This study aimed at characterizing microelastic properties of the ascending aorta wall and lung parenchyma tissues from wild type (WT) and age-matched Fbn1 hypomorphic mic...

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Detalhes bibliográficos
Publicado no:Ann Biomed Eng
Main Authors: Lee, Jia-Jye, Galatioto, Josephine, Rao, Satish, Ramirez, Francesco, Costa, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880286/
https://ncbi.nlm.nih.gov/pubmed/27090893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-016-1616-4
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