Antibody-modified liposomes for tumor-targeting delivery of timosaponin AIII

INTRODUCTION: Timosaponin AIII (TAIII), as a steroid saponin in Anemarrhena asphodeloides, has favorable potential as an antitumor candidate. However, its hydrophobicity and low bioavailability severely limit its in vivo antitumor efficacy. METHODS: To overcome this drawback, TAIII-loaded liposomes...

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Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Lu, Lu, Ding, Yue, Zhang, Yong, Ho, Rodney JY, Zhao, Yuan, Zhang, Tong, Guo, Chunrong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880182/
https://ncbi.nlm.nih.gov/pubmed/29636610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S153107
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