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What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans?: Consideration of Strategies to Improve the Value of Animal Models

Animal models are an essential feature of the vaccine design toolkit. Although animal models have been invaluable in delineating the mechanisms of immune function, their precision in predicting how well specific vaccines work in humans is often suboptimal. There are, of course, many obvious species...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Perspect Biol
Autores principales: Herati, Ramin Sedaghat, Wherry, E. John
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880169/
https://ncbi.nlm.nih.gov/pubmed/28348037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031583
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