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What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans?: Consideration of Strategies to Improve the Value of Animal Models

Animal models are an essential feature of the vaccine design toolkit. Although animal models have been invaluable in delineating the mechanisms of immune function, their precision in predicting how well specific vaccines work in humans is often suboptimal. There are, of course, many obvious species...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Biol
Main Authors: Herati, Ramin Sedaghat, Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880169/
https://ncbi.nlm.nih.gov/pubmed/28348037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031583
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