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What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans?: Reevaluating the Potential of Mouse Models for the Human Immune System

Much of what we understand about immunology, including the response to vaccines, come from studies in mice because they provide many practical advantages compared with research in higher mammals and humans. Nevertheless, modalities for preventing or treating disease do not always translate from mous...

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Veröffentlicht in:Cold Spring Harb Perspect Biol
Hauptverfasser: Jameson, Stephen C., Masopust, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880167/
https://ncbi.nlm.nih.gov/pubmed/28348039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a029132
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