A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures

Breast cancer mortality predominantly results from dormant micrometastases that emerge as fatal outgrowths years after initial diagnosis. In order to gain insights concerning factors associated with emergence of liver metastases, we recreated spontaneous dormancy in an all-human ex vivo hepatic micr...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Clark, Amanda M., Kumar, Manu P., Wheeler, Sarah E., Young, Carissa L., Venkataramanan, Raman, Stolz, Donna B., Griffith, Linda G., Lauffenburger, Douglas A., Wells, Alan
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880110/
https://ncbi.nlm.nih.gov/pubmed/29353230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000370
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