A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures

Breast cancer mortality predominantly results from dormant micrometastases that emerge as fatal outgrowths years after initial diagnosis. In order to gain insights concerning factors associated with emergence of liver metastases, we recreated spontaneous dormancy in an all-human ex vivo hepatic micr...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Clark, Amanda M., Kumar, Manu P., Wheeler, Sarah E., Young, Carissa L., Venkataramanan, Raman, Stolz, Donna B., Griffith, Linda G., Lauffenburger, Douglas A., Wells, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880110/
https://ncbi.nlm.nih.gov/pubmed/29353230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000370
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