A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures

Breast cancer mortality predominantly results from dormant micrometastases that emerge as fatal outgrowths years after initial diagnosis. In order to gain insights concerning factors associated with emergence of liver metastases, we recreated spontaneous dormancy in an all-human ex vivo hepatic micr...

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Publicat a:Mol Cell Proteomics
Autors principals: Clark, Amanda M., Kumar, Manu P., Wheeler, Sarah E., Young, Carissa L., Venkataramanan, Raman, Stolz, Donna B., Griffith, Linda G., Lauffenburger, Douglas A., Wells, Alan
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880110/
https://ncbi.nlm.nih.gov/pubmed/29353230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000370
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